Manage the symptoms

Lubricates

Hyaluronic acid

A lubricating injection that reduces friction inside a worn joint. Well established, straightforward, and the lowest-cost of the four treatments we offer.

From
£600To confirm
How long it lasts
Around six months
What is left behind
Absorbed by the body
Cutaway knee joint showing cartilage thinning, narrowed joint space and marginal bone change
Hyaluronic acid works in the fluid around the joint surfaces. It does not change the cartilage itself.

Where it sits

Hyaluronic acid sits in the manage the symptoms half of what we offer.

Treats how the joint feels. The surface itself is left as it is. Across the spectrum of wear, it may be considered from early wear to diffuse wear.

Healthy
Early wear
Diffuse wear
Bone on bone

The usual first step, and the shortest acting of the four.

What it is

What it is

Hyaluronic acid occurs naturally in the fluid inside your joints, where it acts as a lubricant and a shock absorber. In an osteoarthritic joint, that fluid thins and loses much of its cushioning quality.

A hyaluronic acid injection, sometimes called viscosupplementation, tops that fluid back up. It is delivered directly into the joint, usually under ultrasound guidance so it goes exactly where it is needed. It is available as a single injection or as a course, depending on the preparation used.

What it aims to do

What it does

  • Reduces friction between the joint surfaces
  • Eases day-to-day pain and stiffness
  • Can make movement and exercise more comfortable, which helps everything else

What it does not do

  • It does not rebuild or repair cartilage
  • It does not stop osteoarthritis progressing
  • It is not permanent, and is absorbed by the body over months

Who it may suit

Who may be considered

  • Early to moderate osteoarthritis, where the joint is worn but not severely so
  • People who want to try the least invasive and least expensive option first
  • People for whom anti-inflammatory medication is unsuitable or has stopped helping
  • Joints including the knee, hip and shoulder

None of this replaces an assessment. Suitability is confirmed on examination and imaging, never from a web page.

When another fits better

When something else is the better answer

Arthrosamid

If you do not want to keep repeating injections. Arthrosamid stays in the joint and is expected to last years rather than months.

ChondroFiller Injection

If the goal is to support the worn surface itself rather than to lubricate around it.

An assessment first

If the joint locks, catches or gives way, which points to something mechanical that no injection addresses.

The procedure

How it is done

  1. 01

    Assessment

    A doctor examines the joint and reviews any imaging you already have, to confirm the pattern of wear and that an injection is reasonable.

  2. 02

    Preparation

    An outpatient appointment. No fasting, no general anaesthetic, and you can drive yourself in.

  3. 03

    The injection

    The joint is cleaned and the injection placed into the joint space, usually with ultrasound guidance to confirm position.

  4. 04

    Straight afterwards

    You walk out the same day. Most people go back to normal activity almost immediately.

Antibiotic cover is provided before treatment as part of the clinic infection-prevention protocol, alongside sterile technique.

Recovery

Recovery and what to expect

Most people are back to normal activity the same day, with a short period of taking it easy on the joint.

Relief is not instant. Hyaluronic acid typically takes a few weeks to take full effect, and relief then lasts around six months. Some people get longer, some shorter, and some notice very little difference at all.

It can be repeated. If it worked well the first time, repeating it is reasonable. If it did not help at all, repeating it usually is not the answer, and that is worth saying at your review.

An adult gardening comfortably on a spring afternoon

Risks

Risks and side effects

  • Temporary pain, swelling or warmth in the joint for a day or two afterwards
  • A small flare in the first 24 to 48 hours
  • Infection, which is rare but serious, and the reason for sterile technique and antibiotic cover
  • No benefit at all in a proportion of people

Evidence

What the evidence shows

Hyaluronic acid is one of the most studied injections in osteoarthritis, with decades of clinical use behind it. The consistent finding is modest pain relief over a period of months in mild to moderate disease.

Limitations

The evidence is mixed rather than uniformly positive, and national guidance in some countries does not recommend it routinely. Benefit varies a lot between individuals, and it is less likely to help in a severely worn joint. We would rather say that plainly than oversell it.

Price

What it costs, and where

Included

£600To confirm

  • Consultation
  • Ultrasound-guided injection
  • One follow-up review

Charged separately: imaging

Available at

  • SleafordTo confirm

    London Road, Silk Willoughby, Sleaford, NG34 8NY

  • GranthamTo confirm

    The Old Barracks, Sandon Road, Grantham, NG31 9AS

See all clinics

Compare

How it compares with the other three

Descriptive, not a ranking. Each of these does a different job.

Manage the symptoms

Hyaluronic acid

What it does
Lubricates
Main purpose
Lubrication and symptom relief
Pattern of wear
early wear to diffuse wear
How long it lasts
Around six months
What is left behind
Absorbed by the body
Joints
Knee, Hip, Shoulder
Important limitation
The usual first step, and the shortest acting of the four.
From
£600To confirm

Manage the symptoms

Arthrosamid®

What it does
Cushions
Main purpose
Longer-term symptom management
Pattern of wear
early wear to bone on bone
How long it lasts
Several years from one injection
What is left behind
Stays in the joint, not absorbed
Joints
Knee
Important limitation
Acting early suits it well. At bone on bone it eases pain but changes nothing structurally.
From
£2,400To confirm

Change the surface

Mytocel MSK

What it does
Regenerates
Main purpose
Autologous regenerative pathway
Pattern of wear
early wear to diffuse wear
How long it lasts
Builds over months from one session
What is left behind
Your own tissue
Joints
Knee, Thumb base
Important limitation
Best suited to earlier wear on its own. For more advanced wear it is used inside a fuller approach rather than by itself.
From
£3,000To confirm

Change the surface

ChondroFiller Injection®

What it does
Rebuilds
Main purpose
Collagen scaffold across worn surfaces
Pattern of wear
early wear to bone on bone
How long it lasts
Builds over six to twelve months
What is left behind
Resorbs, leaving your own tissue
Joints
Knee, Hip, Shoulder, Ankle, Elbow, Hand, Wrist
Important limitation
The widest range of the four. At bone on bone it is usually combined with another treatment, or weighed against replacement.
From
£3,500To confirm

This comparison describes what each treatment is for. It is not a ranking, and it cannot tell you which one suits your joint. That is decided at assessment, on examination and imaging.

Questions

Common questions

How long does it last?
Typically around six months. It varies between people, and it tends to give less in a more worn joint.
How soon will I feel something?
Usually a few weeks rather than a few days. If you need faster relief, say so at your assessment, because a different approach may suit you better.
Can I have it more than once?
Yes, if it helped. If it did nothing the first time, repeating it is not usually the right recommendation.
Is it the same as a steroid injection?
No. A steroid injection settles inflammation quickly but fades within weeks. Hyaluronic acid works on lubrication and takes longer to build, but lasts longer.

Other treatments

Find out whether Hyaluronic acid fits your joint.

An assessment looks at the joint, the imaging and what you want back, then tells you honestly which of the four fits, or whether none of them does.

Reviewed by the AMSK clinical teamReviewer to name · Last reviewed 27 July 2026

This page is general information and does not replace an individual clinical assessment. Individual outcomes vary.